David Molloy, 54, was last seen by his sister at 11am at her home in the Paisley's Kilnside Road.
Mr Molloy is described as white, 6ft and slim. He has grey hair and a moustache and was wearing a yellow jacket with navy and red dashes and jeans.
Mr Molloy may be driving a black Renault Clio, with the registration number SG56 VEX.
Police have been carrying out an extensive search of the local area, making door to door enquiries and speaking to family and friends in an effort to trace Mr Molloy but so far there have been no further sightings of him.
Inspector Eddie Gray of Paisley Police Office said: "Mr Molloy's wife and family are obviously growing concerned as his disappearance is completely out of character.
"He had recently been under some financial pressure.
"I would ask anyone who has seen David or knows of his whereabouts, to contact Paisley Police Office on Office on 0141 532 5900 or their local police office as a matter of urgency.
"I would also ask if he is able, that Mr Molloy himself contact police to assure us that